Week 10 of the 2021 NFL schedule culminates with a Monday Night Football game between the and at Levi's Stadium. The Rams (7-2) are looking to join Arizona and Green Bay (8-2) atop the NFC with a win and are coming off a lo s to Tenne see. Meanwhile, the 49ers (3-5) have lost five of their last six games and are just a half-game ahead of Cordarrelle Patterson Jersey last place Seattle in the NFC West. San Francisco has lost eight straight games, including three that were played in Glendale, Ariz., last year due to COVID-19 restrictions.Kickoff is set for 8:15 p.m. ET. Los Angeles is a 3.5-point favorite in the latest Rams vs. 49ers odds from Caesars Sportsbook, while the Over-Under for total points scored is 50.5. Before you make any 49ers vs. Rams picks of your own, you need to .White, a CBS Sports Prince Amukamara Jersey fantasy and gambling editor, ended the 2020 season on an 80-59 run on all , returning more than $1,400 during that span. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest.In addition, White is an amazing 37-19-1 on his last 57 against-the-spread picks involving the Rams, returning $1,576 to $100 players. Anyone who has followed him is way up. Now, he has locked in on and Jim McMahon Jersey released a confident against-the-spread pick. . Here are the and trends for 49ers vs. Rams:Rams vs. 49ers spread: Los Angeles -3.5Rams vs. 49ers Over-Under: 50.5 pointsRams vs. 49ers money line: Los Angeles -190, San Francisco +160LAR: QB leads the league in pa sing yards (2,771)SF: WR ranks second in the NFL in receiving yards (882)Los Angeles has a significant edge in turnovers entering the game. The Rams are tied for sixth in the NFL in turnover margin, having forced 14 takeaways while turning the ball over just five times themselves. The 49ers have committed 14 turnovers while forcing just five, and their minus-nine turnover margin is the third worst in the league. Only the and are worse.In addition, quarterback Matthew Stafford has been stellar in his first season in L.A. The former Detroit quarterback leads the NFL in pa ser rating (111.0) and ranks third in pa sing yards per game (307.9) and pa sing touchdowns (23). His 68.2 completion percentage is the best of his career. San Francisco has dominated the series against the Rams recently. The 49ers have won the past four meetings between the teams and the past two in Santa Clara. San Francisco's average margin of victory in Cody Whitehair Jersey those games is 6.8 points.In addition, the 49ers face Rams quarterback Matthew Stafford, who is coming off his worst game of the season. In the Sunday night lo s to the , Stafford was sacked a season-high five times. He also had his first multi-interception game of the season and averaged 6.1 yards per attempt, his fewest in a game this season.White has analyzed this matchup and while we can tell you he's leaning Under the total, he has discovered a crucial x-factor that makes one side of Dan Hampton Jersey the spread a must-back. . Who wins 49ers vs. Rams on Monday Night Football? And what critical factor makes one side of the spread a must-back? , and find out.